John Travolta
James
Acting
Kirstie Alley
Mollie
Acting
Olympia Dukakis
Rosie
Acting
George Segal
Albert
Acting
Abe Vigoda
Grandpa
Acting
Bruce Willis
Mikey (voice)
Acting
Twink Caplan
Rona
Acting
Jason Schaller
Mikey
Acting
Jaryd Waterhouse
Mikey
Acting
Jacob Haines
Mikey
Acting
Christopher Aydon
Mikey
Acting
Joy Boushel
Melissa
Acting
Don S. Davis
Dr. Fleischer
Acting
Louis Heckerling
Lou
Acting
Brenda Crichlow
Secretary
Acting
Andrea Mann
Salesgirl
Acting
Douglas Tuck
Cab Stealer
Acting
Alex Bruhanski
Street Worker
Acting
Casey Grant
Admitting Clerk
Production
Oscar B. Ramos
Hospital Worker
Acting
Aurelio Dinunzio
Orderly
Acting
Jeff Irvine
Admitting Doctor
Acting
Shirley Barclay
Nurse
Acting
William B. Davis
Drug Doctor
Acting
David Berner
Mr. Impatience
Acting
Jerry Wasserman
Mr. Anal
Acting
Daliah Novak
Carrie
Acting
Zena Darawalla
Lupe
Acting
Nicholas Rice
Harry
Acting
Neal Israel
Mr. Ross
Directing
Blu Mankuma
Director
Acting
William Britos
Home Orderly
Acting
Dee Jay Jackson
Burly Orderly
Acting
Ida Berner
Lady
Acting
Bea Cartmell
Lady
Acting
Eleanor Maines
Lady
Acting
Mollie Heckerling
Little Girl
Acting
Ryan McIntosh
Little Boy
Acting
Gerry Bean
Pilot Friend
Acting
Deryl Hayes
Pilot Friend
Acting
Enid Saunders
Ester
Acting
Nicole Stevens
Silly Baby
Acting
Christy Smith
Baby Megan
Acting
Sabrina Bailey
Sand Box Baby
Acting
Farah Abassi
Chatting Baby
Acting
Amber Brownmiller
Blowing Kiss Baby
Acting
Ariel Perryman
Nursery Baby
Acting
Nigel John Crowe
Nursery Baby
Acting
Michael Joseph Materi
Nursery Baby
Acting
Joan Rivers
Julie (voice) (uncredited)
Acting
Aaron Jefford
Fireman (uncredited)
Acting