Meg Ryan

Kathleen Kelly

Acting

Tom Hanks

Joe Fox

Acting

Greg Kinnear

Frank Navasky

Acting

Heather Burns

Christina Plutzker

Acting

Parker Posey

Patricia Eden

Acting

Dave Chappelle

Kevin Jackson

Acting

Jean Stapleton

Birdie Conrad

Acting

Steve Zahn

George Pappas

Acting

Dabney Coleman

Nelson Fox

Acting

John Randolph

Schulyer Fox

Acting

Hallee Hirsh

Annabelle Fox

Acting

Jeffrey Scaperrotta

Matt Fox

Acting

Cara Seymour

Gillian Quinn

Acting

Katie Finneran

Maureen, the Nanny

Acting

Michael Badalucco

Charlie

Acting

Deborah Rush

Veronica Cash

Acting

Veanne Cox

Miranda Margulies

Acting

Bruce Jay Friedman

Vince Mancini

Writing

Sara Ramirez

Rose, Zabars Cashier

Acting

Howard Spiegel

Henry, Zabars Shopper

Acting

Diane Sokolow

Zabars Shopper

Production

Julie Kass

Zabars Shopper

Acting

Reiko Aylesworth

Thanksgiving Guest

Acting

Katie Sagona

Young Kathleen Kelly

Acting

Kathryn Meisle

Cecilia Kelly

Acting

Nina Zoie Lam

T.V. Reporter

Acting

Maggie Murphy

Theater Patron

Directing

Michelle Blakely

Shopper

Acting

Meredith White

Shopper

Acting

Dianne Dreyer

Shopper

Directing

Julie Galdieri

Shopper

Acting

Leila Nichols

Shopper

Acting

Mary A. Kelly

Fox Books Shopper

Directing

Chris Messina

Fox Salesperson

Acting

Ronobir Lahiri

Man at Cafe Lalo

Acting

André Sogliuzzo

Waiter at Lalo

Acting

Peter A. Mian

Capeman

Crew

Richard Cohen

Starbucks Customer

Acting

Enzo Angileri

Starbucks Customer

Costume & Make-Up

Nick Brown

Juggler

Acting

Ann Fleuchaus

Sarah Mancini

Acting

Neil Bonin

Party Guest

Acting

Bill McHugh

Party Guest

Acting

Santiago Quinones

Decorator

Acting

Lynn Grossman

Yvette Fox

Writing

Dolores Sirianni

Mother of Twins

Acting

Nicole Bernadette

Florist

Acting

Jane Adams

Sydney Anne (uncredited)

Acting

Cecelia Antoinette

Restaurant Patron (uncredited)

Acting

Elwood Edwards

Online 'You've Got Mail' Voice (voice) (uncredited)

Acting

Alfonso Gomez-Rejon

Party Guest (uncredited)

Directing

Gideon Jacobs

Young Joe Fox (uncredited)

Acting

Brick Mason

Man Letting Joe Fox in (uncredited)

Art

Scott Mullin

Male Runner (uncredited)

Acting

Logan Steinhardt

Kid in Bookstore (uncredited)

Production

Anthony Welch

Business Executive (uncredited)

Acting