Bill Murray
Garfield (voice)
Acting
Breckin Meyer
Jon
Acting
Jennifer Love Hewitt
Liz
Acting
Stephen Tobolowsky
Happy Chapman
Acting
Evan Arnold
Wendell
Acting
Mark Christopher Lawrence
Christopher Mello
Acting
Jimmy Kimmel
Spanky (voice)
Acting
Debra Messing
Arlene (voice)
Acting
Nick Cannon
Louis (voice)
Acting
Alan Cumming
Persnikitty (voice)
Acting
Brad Garrett
Luca (voice)
Acting
David Eigenberg
Nermal (voice)
Acting
Jerry Hauck
Cop
Acting
Richard Kind
Dad Rat (voice)
Acting
Vanessa Campbell
Miss Ace Hardware
Acting
Daamen J. Krall
Announcer
Acting
Alyson Stoner
Kid Rat (voice)
Acting
Rufus Gifford
Dog Owner #1
Production
Randee Reicher
Dog Owner #2
Acting
Eve Brent
Mrs. Baker
Acting
Bill Hoag
Roy the Lodge Member
Acting
Susan Moore
Dog Owner #4
Crew
Ben Kronen
Older Man
Acting
Michael Monks
Deputy Hopkins
Acting
Mel Rodriguez
Security Officer
Acting
Ryan McKasson
Dog Owner #3
Acting
Juliette Goglia
Little Girl
Acting
Joseph Edward Taylor
Frank
Acting
Crystal the Monkey
Pet Monkey (uncredited)
Acting