Kate Beckinsale
Selene
Acting
Stephen Rea
Dr. Jacob Lane
Acting
Michael Ealy
Detective Sebastian
Acting
Theo James
David
Acting
India Eisley
Eve
Acting
Charles Dance
Thomas
Acting
Sandrine Holt
Lida
Acting
Sanny van Heteren
British newscaster
Acting
Jacob Blair
Kolb (Officer)
Acting
Robert Lawrenson
Waterfront Cop
Acting
Kurt Max Runte
Leader of the Troop
Acting
Marvin Duerkholz
Lestroy
Acting
Ron Wear
Jack Fletcher
Acting
Richard Cetrone
Lycan 1
Acting
Dan Payne
Lycan 2
Acting
Mark Gibbon
Announcing Guard
Acting
Benita Ha
Surgical Nurse
Acting
Tyler McClendon
Scientist
Acting
Panou
Old City Cop #1
Acting
Ian Rozylo
Old City Cop #2
Acting
Kristen Holden-Ried
Quint Lane
Acting
John Innes
Medical Supervisor
Acting
Lee Majdoub
Desk Guard
Acting
Catlin Adams
Olivia
Acting
Adam Greydon Reid
Med Tech
Acting
Christian Tessier
Security Guard #1
Acting
Wes Bentley
Antigen Scientist (uncredited)
Acting
Scott Speedman
Michael (archive footage) (uncredited)
Acting
Joe Censoplano
Cadillac Driver (uncredited)
Acting
Preston Cook
Antigen Surgeon (uncredited)
Acting