Roy Scheider
Dr. Heywood Floyd
Acting
John Lithgow
Dr. Walter Curnow
Acting
Helen Mirren
Tanya Kirbuk
Acting
Bob Balaban
Dr. R. Chandra
Acting
Keir Dullea
Dr. David Bowman
Acting
Douglas Rain
HAL 9000 (voice)
Acting
Madolyn Smith Osborne
Caroline Floyd
Acting
Savely Kramarov
Dr. Vladimir Rudenko
Acting
Taliesin Jaffe
Christopher Floyd
Acting
James McEachin
Victor Milson
Acting
Mary Jo Deschanel
Betty Fernandez
Acting
Elya Baskin
Maxim Brailovsky
Acting
Dana Elcar
Dimitri Moisevitch
Acting
Oleg Rudnik
Dr. Vasili Orlov
Acting
Natasha Shneider
Irina Yakunina
Acting
Vladimir Skomarovsky
Yuri Svetlanov
Acting
Victor Steinbach
Nikolaj Ternovsky
Acting
Candice Bergen
SAL 9000 (voice)
Acting
Gene McGarr
Commercial Announcer
Acting
Herta Ware
Jessie Bowman
Acting
Jan Tříska
Alexander Kovalev
Acting
Larry Carroll
Anchorman on TV
Acting
Cheryl Carter
Nurse
Acting
Ron Recasner
Hospital Neurosurgeon
Acting
Robert Lesser
Dr. Hirsch
Acting
Delana Michaels
Commercial Announcer
Acting
Arthur C. Clarke
Man on Park Bench (uncredited)
Writing