James Marsden
Diggs (voice)
Acting
Nick Nolte
Butch (voice)
Acting
Christina Applegate
Catherine (voice)
Acting
Bette Midler
Kitty Galore (voice)
Acting
Pascale Hutton
Jackie
Acting
Katt Williams
Seamus (voice)
Acting
Neil Patrick Harris
Lou (voice)
Acting
Sean Hayes
Mr. Tinkles (voice)
Acting
Wallace Shawn
Calico (voice)
Acting
Roger Moore
Tab Lazenby (voice)
Acting
Joe Pantoliano
Peek (voice)
Acting
Michael Clarke Duncan
Sam (voice)
Acting
Chris O'Donnell
Shane
Acting
Jack McBrayer
Chuck
Acting
Fred Armisen
Freidrich
Acting
Kiernan Shipka
Little Girl
Acting
Paul Rodríguez
Crazy Carlito (voice)
Acting
J.K. Simmons
Gruff K-9 (voice)
Acting
Grey DeLisle
Security Bulldog/Catherine's Niece/Cat Spy Analyst
Acting
E. G. Daily
Scrumptious / Patches / Catherine's Niece (voice)
Acting
Phil LaMarr
Paws / Cat Spy Analyst (voice)
Acting
Michael Beattie
Angus MacDougall (voice)
Acting
Jeff Bennett
Duncan MacDougall (voice)
Acting
Malcolm Stewart
Captain Flemming
Acting
Dawn Chubai
Reporter
Acting
Keith Dallas
Coit Tower Guard
Acting
Len Morganti
Rex (voice)
Art
Betty Phillips
Cat Lady
Acting
Christopher Lee Parson
Hep Cat / Cat Spy Analyst (voice)
Acting
Bumper Robinson
Cool Cat / Dog Killa / Cat Spy Analyst / Slim (voice)
Acting
Rick D. Wasserman
Rocky (voice)
Acting
Roger L. Jackson
Inmate Fat Cat (voice)
Acting
Bonnie Cahoon
Dog HQ PA / Catherine's Niece (voice)
Acting
André Sogliuzzo
Snobby K-9 (voice)
Acting
Carlos Alazraqui
Cat Gunner / Cat Spy Analyst (voice)
Acting
Grey DeLisle
Security Bulldog / Catherine's Niece / Cat Spy Analyst (voice)
Acting
Ingrid Tesch
Mom
Acting
Amitai Marmorstein
Playland Worker
Acting
Robert Hewko
Old Man
Acting
Mark Burgess
Used Car Salesman
Acting
Sage Brocklebank
Park Patron
Acting