Gena Rowlands
Ivy
Acting
Tony Shalhoub
Misha Vilyenkov
Acting
Cheech Marin
Ignacio
Acting
Bruce Davison
Dr. Reingold
Acting
Trini Alvarado
Adult Marie Alweather
Acting
Jay Mohr
Benny / Paulie (voice)
Acting
Buddy Hackett
Artie
Acting
Hallie Eisenberg
Marie Alweather
Acting
Matt Craven
Warren Alweather
Acting
Bill Cobbs
Virgil the Janitor
Acting
Tia Texada
Ruby / Lupe (voice)
Acting
Laura Harrington
Lila Alweather
Acting
Peter Basch
Graduate Student #1
Acting
Emily Mura-Smith
Graduate Student #2
Acting
Hal Robinson
Grandpa
Acting
Tamara Zook
Speech Therapist
Acting
Nicole Chamberlain
Shirley
Acting
Charles Parks
Gerald
Acting
Seth Mumy
Jeremy
Acting
Dig Wayne
Research Assistant #1
Acting
Michael Leydon Campbell
Research Assistant #2
Acting
Kristie Transeau
Veterinarian
Acting
Francesca Federico-O'Murchu
Molly
Acting
Jerry Winsett
Mr. Tauper
Acting
Bud Cox
Ivy's Doctor
Acting