Gena Rowlands

Ivy

Acting

Tony Shalhoub

Misha Vilyenkov

Acting

Cheech Marin

Ignacio

Acting

Bruce Davison

Dr. Reingold

Acting

Trini Alvarado

Adult Marie Alweather

Acting

Jay Mohr

Benny / Paulie (voice)

Acting

Buddy Hackett

Artie

Acting

Hallie Eisenberg

Marie Alweather

Acting

Matt Craven

Warren Alweather

Acting

Bill Cobbs

Virgil the Janitor

Acting

Tia Texada

Ruby / Lupe (voice)

Acting

Laura Harrington

Lila Alweather

Acting

Peter Basch

Graduate Student #1

Acting

Emily Mura-Smith

Graduate Student #2

Acting

Hal Robinson

Grandpa

Acting

Tamara Zook

Speech Therapist

Acting

Nicole Chamberlain

Shirley

Acting

Charles Parks

Gerald

Acting

Seth Mumy

Jeremy

Acting

Dig Wayne

Research Assistant #1

Acting

Michael Leydon Campbell

Research Assistant #2

Acting

Kristie Transeau

Veterinarian

Acting

Francesca Federico-O'Murchu

Molly

Acting

Jerry Winsett

Mr. Tauper

Acting

Bud Cox

Ivy's Doctor

Acting

Josh Cruze

Cantina Singer

Acting