Sarah Silverman
Self
Acting
Nathan Barnatt
Homeless Man (segment "Lisa")
Acting
Lauren Lapkus
Girl 5 (segment "Lisa")
Acting
John C. Reilly
Father (segment "Ham")
Acting
Laura Silverman
Self (segment "Knickers")
Acting
Seth Rogen
Officer Durand (segment "Knickers")
Acting
Jade Catta-Preta
Mother (segment "Lisa")
Acting
Natasha Leggero
Girl 2 (segment "Lisa")
Acting
Shelby Fero
Girl 1 (segment "Lisa")
Acting
Nathan Fielder
Self (segment "Retro Video Arcade")
Acting
David Dineen-Porter
Self (segment "Retro Video Arcade")
Acting
Kyle Dunnigan
Self
Acting
Michael Daniel Cassady
Self (segment "Lisa")
Acting
Brett Gelman
Self
Acting
Emily Maya Mills
Girl 6 (segment "Lisa")
Acting
Nick Rutherford
Father (segment "Lisa")
Acting
Rob Schrab
Self
Directing
Paul Rust
Self (segment "Lisa")
Acting
Stoney Sharp
Self
Directing
Armen Weitzman
Mailman
Acting
Kulap Vilaysack
Girl 3 (segment "Lisa")
Acting
Eric Wareheim
Self
Acting
Harris Wittels
Scientist 1 (segment "CCDF")
Acting
Charlyne Yi
Self
Acting
Tig Notaro
Girl 4 (segment "Lisa")
Acting
Todd Glass
Self
Acting
Grace Helbig
Bride 5 (segment "Absorption")
Acting
2 Chainz
Self (segment "Absorption")
Acting
Casey Ford Alexander
Bad Guy 2 (segment "CCDF")
Acting
Jack Bornoff
Tomato Man (segment "Ham")
Acting
Hailey Boyle
Cashier (segment "Knickers")
Acting
Aaron Chrenen
Cooper (segment "Ginger Orphan Playhouse") (voice)
Writing
Larry A. Davies
Lloyd (segment "Absorption")
Acting
Greg Davis Jr.
Groom 2 (segment "Absorption")
Acting
Donna DuBain
Madame Trinkett (segment "Ginger Orphan Playhouse") (voice)
Production
Trevor Eyster
Bad Guy 1 (segment "CCDF")
Acting
Malinda Farrington
Malinda (segment "Ham")
Acting
Kate Freund
Prostitute (segment "CCDF")
Acting
David Garcia
Bad Guy 3 (segment "CCDF")
Directing
Cyrus Ghahremani
Self
Sound
Hannah Hart
Bride 4 (segment "Absorption")
Acting
Deloris Heard
Customer (segment "Knickers")
Acting
Pamela Immel
Pamela (segment "Ham")
Acting
Zack Kennedy
Band Member 4 (segment "Absorption")
Acting
Keegan-Michael Key
Self (segment "Absorption")
Acting
Ben Lepley
Vacuum Salesman (segment "Ginger Orphan Playhouse") (voice)
Acting
Catherine Lydon
Cashier (segment "Ham")
Acting
Rasika Mathur
Bride 3 (segment "Absorption")
Acting
Kyle Pacek
Son (segment "Ham")
Acting
Sandeep Parikh
Groom 3 (segment "Absorption")
Acting
Jordan Peele
Self (segment "Absorption")
Acting
Issa Rae
Bride 2 (segment "Absorption")
Acting
Ron Ransen
Band Member 1 (segment "Absorption")
Acting
Mike Relm
Self
Directing
Willy Roberts
Taco Truck Worker (segment "CCDF")
Acting
Chase Stewart
Son (segment "Lisa")
Acting
Mark Taormino
Band Member 2 (segment "Absorption")
Acting
Brittani Taylor
Bride 1 (segment "Absorption")
Acting
Aono Tetsuji
Bad Guy 4 (segment "CCDF")
Acting
James Trenton
James (segment "Ham")
Acting
Jack Vale
Groom 1 (segment "Absorption")
Acting