Ed Helms
Rusty Griswold
Acting
Christina Applegate
Debbie Griswold
Acting
Skyler Gisondo
James Griswold
Acting
Steele Stebbins
Kevin Griswold
Acting
Chris Hemsworth
Stone Crandall
Acting
Leslie Mann
Audrey Griswold
Acting
Chevy Chase
Clark Griswold
Acting
Beverly D'Angelo
Ellen Griswold
Acting
Charlie Day
Chad
Acting
Catherine Missal
Adena
Acting
Ron Livingston
Ethan
Acting
Norman Reedus
Trucker
Acting
Keegan-Michael Key
Jack Peterson
Acting
Regina Hall
Nancy Peterson
Acting
Emyri Crutchfield
Sheila Peterson
Acting
Alkoya Brunson
Gary Peterson
Acting
Nick Kroll
Colorado Cop
Acting
Tim Heidecker
Utah Cop
Acting
Kaitlin Olson
Arizona Cop
Acting
Michael Peña
New Mexico Cop
Acting
Hannah Jeter
Ferrari Girl
Acting
David Clennon
Harry Co-Pilot
Acting
Colin Hanks
Jake
Acting
Kirstin Ford
Mom on Plane
Acting
Ethan Maher
Boy on Plane
Acting
Elizabeth Gillies
Heather
Acting
Cristina Squyres
Brooke
Acting
Nadine Avola
Chelsea
Acting
Ryan Cartwright
Terry
Acting
Valerie Payton
Shuttle Driver
Acting
O'Clair Alexander
Husky Lady at Monument
Acting
Miles Doleac
Man on the Monument
Acting
Holly Gardner
Women at Monument
Acting
R.F. Daley
Furious Husband
Acting
Elizabeth Fendrick
Furious Wife
Acting
Michael H. Cole
Male Guest
Acting
Brooke Jaye Taylor
Female Guest
Acting
Matthew Cornwell
Male Guest #2
Acting
Mitchell Warren
Wally World Kid #2
Acting
John Francis Daley
Ride Operator
Writing
Brandon Michael Hale
Gas Station Clerk (uncredited)
Crew
Libby Blake
Boobs (uncredited)
Acting
Rick Ericson
Hawaiian (uncredited)
Acting
Omar Lagudali
Reporter (uncredited)
Acting
Cameron McIntyre
Young James (age 7 / 9) (uncredited)
Acting
Jonathan Goldstein
Hot Tub Guy (uncredited)
Directing
John C. McGinley
Motorbike Cop
Acting