E. G. Daily
Tommy Pickles (voice)
Acting
Nancy Cartwright
Chuckie Finster (voice)
Acting
Kath Soucie
Phil DeVille / Lil DeVille / Betty DeVille (voice)
Acting
Dionne Quan
Kimi Watanabe-Finster (voice)
Acting
Tim Curry
Nigel Thornberry (voice)
Acting
Joe Alaskey
Lou Pickles (voice)
Acting
Tress MacNeille
Charlotte Pickles (voice)
Acting
Michael Bell
Drew Pickles / Charles 'Chaz' Finster, Sr. (voice)
Acting
Julia Kato
Kira Watanabe-Finster (voice)
Acting
Phil Proctor
Howard DeVille (voice)
Acting
Jack Riley
Stuart 'Stu' Pickles (voice)
Acting
Tara Strong
Dil Pickles (voice)
Acting
Cree Summer
Susie Carmichael (voice)
Acting
Cheryl Chase
Angelica Pickels (voice)
Acting
Melanie Chartoff
Didi Pickles (voice)
Acting
Lacey Chabert
Eliza Thornberry (voice)
Acting
Danielle Harris
Debbie Thornberry (voice)
Acting
Jodi Carlisle
Marianne Thornberry (voice)
Acting
Flea
Donnie Thornberry (voice)
Acting
Tom Kane
Darwin (voice)
Acting
Bruce Willis
Spike (voice)
Acting
Tony Jay
Dr. Lipschitz (voice)
Acting
Ethan Phillips
Toa (voice)
Acting
Chrissie Hynde
Siri (voice)
Acting