Sam Rockwell
Darwin the Guinea Pig (voice)
Acting
Jon Favreau
Hurley the Guinea Pig (voice)
Acting
Tracy Morgan
Blaster the Guinea Pig (voice)
Acting
Penélope Cruz
Juarez the Guinea Pig (voice)
Acting
Nicolas Cage
Speckles the Mole (voice)
Acting
Dee Bradley Baker
Mooch the Fly (voice)
Acting
Bill Nighy
Leonard Saber
Acting
Will Arnett
Kip Killian
Acting
Zach Galifianakis
Ben
Acting
Kelli Garner
Marcie
Acting
Steve Buscemi
Bucky the Hamster (voice)
Acting
Jared Lavette
Jared the Skunk (voice)
Acting
Micah Lavette
Micah the Fox (voice)
Acting
Niecy Nash-Betts
Rosalita
Acting
Loudon Wainwright III
Grandpa Goodman
Acting
Tyler Patrick Jones
Connor
Acting
Piper Mackenzie Harris
Penny
Acting
Chris Ellis
NSA Director
Acting
Gabriel Casseus
Carter
Acting
Justin Mentell
Terrell
Acting
Troy Robinson
Agent
Acting
Travis Davis
Agent
Acting
Corey Michael Eubanks
Agent
Acting
Mini Anden
Saber's Assistant
Acting
Camaron Engels
Skateboarder #1 (as Cameron Engels)
Acting
Steve Kelso
Agent
Crew
Max Favreau
Mice (voice)
Acting
James Huang
Agent
Acting
Jack Conley
Agent Trigstad
Acting