Chris Rock
Osmosis Jones (voice)
Acting
Laurence Fishburne
Thrax (voice)
Acting
David Hyde Pierce
Drix (voice)
Acting
Brandy Norwood
Leah (voice)
Acting
William Shatner
Mayor Phlegmming (voice)
Acting
Ron Howard
Tom Colonic (voice)
Directing
Kid Rock
Kidney Rock (voice)
Acting
Bill Murray
Frank Detorre
Acting
Molly Shannon
Mrs. Boyd
Acting
Chris Elliott
Bob
Acting
Elena Franklin
Shane Detorre
Acting
Jonathan Adams
Officer Tom (voice)
Acting
Carlos Alazraqui
Spanish Germ (voice)
Acting
Keith Anthony
Additional Character Voices (voice)
Acting
Eddie Barth
Conductor (voice)
Acting
Sally Brooks
Additional Character Voices (voice)
Acting
Rodger Bumpass
Joe Cramp / Announcer for Nerve News Network (voice)
Acting
Michael Carven
Additional Character Voices (voice)
Acting
Paul Christie
Dan Matter / Germ (voice)
Acting
Janis Dardaris
Additional Character Voices (voice)
Acting
Wendy Dillon
Additional Character Voices (voice)
Acting
Antonio Fargas
Chill the Flu Shot (voice)
Acting
Eddie Frierson
Frank Police Department Officer (voice)
Acting
Donald Fullilove
Doughnut (voice)
Acting
Jackie Gonneau
Additional Character Voices (voice)
Acting
Shannon Gregory
Additional Character Voices (voice)
Acting
Richard Steven Horvitz
Additional Character Voices (voice)
Acting
Rif Hutton
Charlie (voice)
Acting
Art Kimbro
Additional Character Voices (voice)
Acting
Joyce Kurtz
Additional Character Voices (voice)
Acting
Anne Lockhart
Female Red Blood Cell (voice)
Acting
Sherry Lynn
Trudy (voice)
Acting
Danny Mann
Musician Cell (voice)
Acting
Mickie McGowan
Brain Librarian (voice)
Acting
Kenny Olson
Kidney Rock Band (voice)
Acting
Jason Krause
Kidney Rock Band (voice)
Acting
Joe C.
Kidney Rock Band (voice)
Acting
Stefanie Eulinberg
Kidney Rock Band (voice)
Acting
Jimmie Bones
Kidney Rock Band (voice)
Acting
Uncle Kracker
Kidney Rock Band (voice)
Acting
Joel Silver
Police Chief (voice) (uncredited)
Production
David Ossman
Scabies (voice) (uncredited)
Writing
John Melendez
Artie (voice)
Acting
Héctor Mercado
Additional Character Voices (voice)
Acting
Paul Pape
Male Red Blood Cell #2 (voice)
Acting
Marilyn Pasekoff
Additional Character Voices (voice)
Acting
Chris Phillips
Firefighter Doug (voice)
Acting
Lynne Redding
Additional Character Voices (voice)
Production
Al Rodrigo
Frank Police Department Walkie Talkie (voice)
Acting
Herschel Sparber
Bruiser (voice)
Acting
Doug Stone
Police Officer Jamie (voice)
Acting
Steve Susskind
Mob Boss Germ (voice)
Acting
Keri Tombazian
Additional Character Voices (voice)
Acting
Paul Tuerpe
Additional Character Voices (voice)
Acting
Robert Wisdom
Big Germ (voice)
Acting
Danny Murphy
Zookeeper Superintendent
Acting
Jack McCullough
Zookeeper
Acting
Will Dunn
Oyster Boy
Acting
Jackie Flynn
School Janitor
Acting
Kelsey Jordan
Bus Girl #1
Acting
Abe Farrelly
Bus Girl #2
Acting
Jesse Peter
Laughing Boy
Acting
John-Eliot Jordan
Pea Soup Manager
Acting
Nancy Byers
Pea Soup Supervisor
Acting
Kevin J. Flynn
Docky's Clamshack Waiter
Acting
Sean Gildea
Dreamy Photographer
Acting
Kathryn Frick
Nurse #1
Acting
Nikki Tyler-Flynn
Nurse #2
Acting
Elizabeth Jordan
Nurse #3
Acting
Zen Gesner
ER Doctor #1
Acting
Marc Hyman
ER Doctor #2
Writing
Zak Penn
ER Doctor #3
Writing
Diane Conrad
Zoo Visitor or Staff
Acting
Judith Conrad
Zoo Visitor or Staff
Acting
Thomas Jordan
The Zoo Visitor or Staff
Visual Effects
Sydney J. Bartholomew Jr.
Zoo Visitor or Staff
Art
Erica Johnson
Zoo Visitor or Staff
Acting
Bo Cleary
Pea Soup Staff
Acting
Bruce McIntyre
Pea Soup Staff
Acting
Colleen O'Donnell
Docky's Clamshack
Costume & Make-Up
Docky
The Bikini Gang
Acting
Joe Murphy
The Bikini Gang
Acting
Brian Mone
Police Officer
Acting
Sean Fitzgerald
Police Officer
Acting
Grace Costa
ER Nurse
Acting
Emily O’Donnell
School Girl
Acting