Debi Derryberry
James 'Jimmy' Isaac Neutron (voice)
Acting
Megan Cavanagh
Judy Neutron / VOX (voice)
Acting
Mark DeCarlo
Hugh Neutron / Pilot / Arena Guard (voice)
Acting
Jeffrey Garcia
Sheen Estevez (voice)
Acting
Patrick Stewart
King Goobot V (voice)
Acting
Martin Short
Ooblar (voice)
Acting
Frank Welker
Goddard / Poultra (voice)
Acting
Rob Paulsen
Carl Wheezer / Mr. and Mrs. Wheezer / Kid in Classroom (voice)
Acting
Carolyn Lawrence
Cindy Vortex (voice)
Acting
Crystal Scales
Libby Folfax (voice)
Acting
Candi Milo
Nick Dean / Britney / PJ (voice)
Acting
David L. Lander
Yokian Guard / Gus (voice)
Acting
Carlos Alazraqui
Mr. Estevez (voice)
Acting
Jim Cummings
Ultra Lord / Mission Control / General Bob (voice)
Acting
Keith Alcorn
Bobby / Kid / Control Yokian (voice)
Directing
Kimberly Brooks
Zachary / Reporter / Angie / Libby's Mom (voice)
Acting
Andrea Martin
Ms. Winfred Fowl (voice)
Acting
Billy West
Bobby's Twin Brother (voice) / Butch (voice) / Jailbreak Cop (voice) / Old Man Johnson (voice) / Robobarber (voice) / Flurp Announcer (voice) / Yokian Officer (voice) / Anchor Boy (voice) / Guard (voice)
Acting
Mary Hart
Yokian Newscaster #2 (voice)
Acting
Bob Goen
Yokian Newscaster #1 (voice)
Acting
Dee Bradley Baker
Norad Officer (voice)
Acting
Laraine Newman
Hostess (voice)
Acting
John A. Davis
Octapuke Kid / Guard / Bennie (voice)
Production
Paul Greenberg
Guard (voice)
Acting
Mark Menza
Yokian Incubator Operator (voice)
Sound
Jeannie Elias
Little Girl / Camera Person (voice)
Acting
Michael Hagiwara
Chris (voice)
Acting
Richard Allen
Digital Voice (voice)
Acting
Brian Capshaw
Screamer (voice)
Crew
Cheryl Ray
Screamer (voice)
Visual Effects
Matthew Russell
Hyperactive Kid / Arena Yokian (voice)
Visual Effects