Gwyneth Paltrow
Donna Jensen
Acting
Christina Applegate
Christine Montgomery
Acting
Mark Ruffalo
Ted Stewart
Acting
Candice Bergen
Sally Weston
Acting
Joshua Malina
Randy Jones
Acting
Mike Myers
John Witney
Acting
Kelly Preston
Sherry
Acting
Stacey Dash
Angela Samona
Acting
Rob Lowe
Co-Pilot Steve Bench
Acting
Marc Blucas
Tommy Boulay
Acting
Frederick Coffin
Mr. Stewart
Acting
Jon Polito
Roy Roby
Acting
Concetta Tomei
Mrs. Stewart
Acting
Robyn Peterson
Donna's Mom
Acting
Nadia Dajani
Paige
Acting
John Francis Daley
Rodney
Writing
Priscilla Inga Taylor
Janette
Acting
Matt Roth
Greg
Acting
DonnaMarie Recco
Tammy
Acting
Daniel Raymont
British Man
Acting
Connie Sawyer
Grandma Stewart
Acting
David Hayward
Pete
Acting
Chelsey Cole
Donna - 6 Years Old
Acting
Troy Evans
Customer
Acting
Merrilee McCommas
June
Acting
George Kennedy
Passenger Requesting Vodka (uncredited)
Acting
Candice T. Cain
CDG Passenger (uncredited)
Directing
Valentin Siroon
Flight Attendant Trainee (uncredited)
Acting
Jessica Capshaw
Royalty International Flight Attendant (uncredited)
Acting
Mary McNeal
Ted's Study Partner Mary
Acting
Stephanie Miller
TV Interviewer
Acting
Susan Mosher
Senior Flight Attendant
Acting
Victoria Garcia-Kelleher
Clerk #1 (uncredited)
Acting
Stephen Tobolowsky
Frank Thomas (uncredited)
Acting
Anastacia Spiegel
Runway Model at Airport (uncredited)
Acting
Amanda Wycoff
Flight Attendant Trainee (uncredited)
Acting
Dawn-Marie Whelan
Flight Attendant Trainee Anne (uncredited)
Acting
Jeff Yagher
Ghost Rider
Acting
Greg Bronson
Fashion Photographer (uncredited)
Acting
Roark Critchlow
Tennis Pro (uncredited)
Acting
Chad Everett
Jack Weston (uncredited)
Acting
Wayne Federman
Whiskey Sour Man (uncredited)
Acting
Clarinda Ross
Diaper Woman (uncredited)
Acting
Jackie Zane
Passenger in Terminal (uncredited)
Acting